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Diltiazem prices Based on the 2011 American College of Cardiology Foundation/American Heart Association (ACCF/AHA) guideline for the diagnosis and treatment of hypertrophic cardiomyopathy, diltiazem is an effective and recommended alternative agent for the treatment of symptoms (eg, angina, dyspnea) in patients with obstructive or nonobstructive hypertrophic … Diltiazem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders. Diltiazem may also be used for purposes not listed in this medication guide. Related/similar drugs Diltiazem belongs to the class of medicines known as calcium channel blockers (may also be called a calcium channel antagonist). 2. Upsides May be used for the treatment of high blood pressure (hypertension), alone or in combination with other agents for high blood pressure. 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